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sympathomimetic drug : ウィキペディア英語版 | sympathomimetic drug
Sympathomimetic drugs are stimulant compounds which mimic the effects of agonists of the sympathetic nervous system such as the catecholamines. (epinephrine (adrenaline), norepinephrine (noradrenaline), dopamine, etc.) Sympathomimetic drugs are used to treat cardiac arrest and low blood pressure, or even delay premature labor, among other things. These drugs can act through several mechanisms, such as directly activating postsynaptic receptors, blocking breakdown and reuptake of certain neurotransmitters, or stimulating production and release of catecholamines. ==Mechanisms of action== The mechanisms of sympathomimetic drugs can be direct-acting, such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting, such as MAOIs, COMT inhibitors, release stimulants, and reuptake inhibitors that increase the levels of endogenous catecholamines.
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